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I'll start with a weird hormone levels issue I'm having.

Weird high testosterone AND estradiol bloodwork

Been on injectable EV mono for 9 months. For the first 6 months i was taking 2.3mg / 4 days, and for the past 3 months, ive been taking 3.0mg/5 days (very slight increase)

After 3 months, my peak levels (i know, weird nurse) were 250pg/mL E2 and 25ng/dL T.

After 9 months, my peak levels were 450pg/mL E2 and 120 ng/dL T.

I'm getting another bloodwork done in 3 months, both peak and trough this time. Also i'm switching back to 2.3mg EV / 4 days.

I'm wondering if it makes sense to anyone that my E2 is quite high and my T is too high. I expected my peak E2 to be a little higher because 5 vs 4 day cycles but this seems like a lot

Update, I forgot to not take B-complex

So that probably messed with my levels

what ester? i assume EV = estradiol valerate seems aligned with the ups and downs you're experiencing. after switching to enanthate my levels got a lot more stable. would recommend that if you can get your hands on it.

not everyone can get good T suppression on monotheraphy. any reason why no anti androgen?

It was working fine before without AA, it just turns out taking biotin supplements within a few days of hormone bloodwork can fuck up the results. So really I have no idea what my current levels are.

And EV's high peaks and low troughs can be mitigated by taking it often, such as on a 4 day cycle

>>3msc4gkcci226
>And EV's high peaks and low troughs can be mitigated by taking it often, such as on a 4 day cycle
two preparations giving equivalent total estradiol exposure won't necessarily have the same potency, because spikier curves may "waste" some of their peak against saturated estrogen receptors and drop off quickly. this has two effects. the trough you often see with valerate can cause your body to produce T in the absence of estrogen. flatter curves (like enanthate) mitigate this, and are also more efficient per unit of total exposure. since we don't usually have a way to monitor our levels daily flatter and even is generally less risky

not saying you're doing anything wrong - but i'm just someone who is very much concerned about doing the best thing possible

Makes sense. I'm not doing DIY for now and compounding pharms where I am on have EV

finally got access to a vial today while waiting on an order to come through. the market for diy rn feels a little dubious, i'm concerned. i had already missed shots for a few weeks as a result of delays, which hasn't been good.


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